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KMID : 0356720140300060290
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Journal of the Korean Society of Coloproctology
2014 Volume.30 No. 6 p.290 ~ p.293
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Acute Hyponatremia With Seizure and Mental Change After Oral Sodium Picosulfate/Magnesium Citrate Bowel Preparation
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Cho Young-Sun
Nam Kyung-Min
Park Jang-Ho
Byun Sang-Hwan
Ryu Jin-Suck
Kim Hyun-Ju
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Abstract
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Sodium picosulfate/magnesium citrate (Picolight Powder), which is used as a bowel preparation for the colon and the rectum, can cause a severe electrolyte imbalance like hyponatremia. When hyponatremia gets severe or occurs rapidly, it can lead to death due to associated complications. We have experienced a case of hyponatremia associated with seizure and loss of consciousness in a 76-year-old woman, who took sodium picosulfate/magnesium citrate as a bowel preparation for colonoscopy. She was taking thiazide and synthroid for the treatment of hypertension and hypothyroidism, respectively, and she had other underlying medical conditions such as a history of seizure and dementia. Following the diagnosis of hyponatremia, we used an intravenous injection of 3% NaCl to normalize the sodium level in her serum, and her associated symptoms soon disappeared.
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KEYWORD
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Picosulfate sodium, Bowel preparation, Hyponatremia, Seizures, Colonoscopy
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